Sure Sinus was created after our founder found that his own symptoms of chronic sinusitis had become so serious that he considered walking away from his passion for business. Instead of giving up, he put his head down to personally research and navigate his way through the maze of sinusitis cures. It was during this period that he discovered research that pointed him towards probiotics as a potential way to help relieve the chronic symptoms of  sinusitis.

After several years of research, he was able to settle on his own proprietary mixture of probiotic strains of Lactobacillus that, per his own biohacking and experimentation, helped alleviate the myriad symptoms of his chronic sinusitis. Marc had put together a combination that changed his life—an actual, tangible and consistent solution for just about anyone suffering from both acute and chronic versions of sinusitis.

Since then, he has had his eyes up and his clear-as-day nose to the ground building out Sure Sinus as a product that is able to help millions.

These bacteria produce vitamins and nutrients, boost immune response and protect against carcinogens and unhealthy bacteria.

A diverse mixture is very important to a healthy biome.

Sure Sinus is based on revolutionary research into the composition, modulation, and health of the human sinus biome. Abreu, Nicole A, et al. “Sinus Microbiome Diversity Depletion and Corynebacterium Tuberculostearicum Enrichment Mediates Rhinosinusitis.” Science Translational Medicine, U.S. National Library of Medicine, 12 Sept. 2012, www.ncbi.nlm.nih.gov/pubmed/25819063
Mahdavinia, M, et al. “A Comprehensive Review of the Nasal Microbiome in Chronic Rhinosinusitis (CRS).” Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology, U.S. National Library of Medicine, Jan. 2016, www.ncbi.nlm.nih.gov/pubmed/25819063

Ramakrishnan, Vijay R, et al. “Sinus Microbiota Varies among Chronic Rhinosinusitis Phenotypes and Predicts Surgical Outcome.” The Journal of Allergy and Clinical Immunology, U.S. National Library of Medicine, Aug. 2015, www.ncbi.nlm.nih.gov/pubmed/25819063

Vickery, Thad W, and Vijay R Ramakrishnan. “Bacterial Pathogens and the Microbiome.” Otolaryngologic Clinics of North America, U.S. National Library of Medicine, Feb. 2017, www.ncbi.nlm.nih.gov/pubmed/27888914

Scientific Studies

Sure Sinus manipulates the sinus microbiome to restore immune homeostasis. Sure Sinus works to prevent dysbiosis, or microbial imbalance, within your sinus microbiome. It works with your body to solidify the mucosal immunology of the respiratory membranes in your sinus cavity.

The nature and composition of bacteria present in the sinus biome are important contributors to the development of host defenses against infection and allergic reaction. Data shows that probiotic supplementation modulates immune responses and can help lessen symptoms. Probiotics help your body find the balance between necessary and excessive defense mechanisms.

Using scientifically-backed ingredients, Sure Sinus is primarily composed of 4 different strains of Lactobacilli. Beneficial varieties of this bacteria produce vitamins and nutrients, boost immune response and protect against carcinogens and unhealthy bacteria.

The mixture of species developed for Sure Sinus are all naturally part of the human sinus biome, as either a keystone (has a disproportionately large effect on the community), a pioneer (are the first to colonize the niche after a disruption), or a dominant (a relatively high abundance in most people) species. The right mixture is very important to a healthy biome.

The chosen strains have been found to be safe, and conducive to restoring your body’s sinus biome to its native state. Having a sinus biome that is out of balance leads to many common symptoms of both acute and chronic sinusitis. Scientific studies have shown that sinus inflammation is associated with decreased sinus bacterial diversity and the then collateral enrichment of specific sinus pathogens. The included species have been shown to competitively exclude the habitation of certain harmful bacteria.

The probiotics within Sure Sinus primarily act through the production of antimicrobial compounds. For example, one included strain produces the protein reuterin, which acts as an antimicrobial compound by inducing oxidative stress in competing bacteria. The effects of this protein are aimed at eliminating competing microbes, giving the good bacteria an advantage in righting the biome.

Intranasal administration is key in regulating respiratory immune responses. Probiotic administration directly into the sinus biome can influence the host composition and function via antimicrobial production, changing PH levels, or through competitive colonization.